MetaCyc Pathway: superpathway of pyrimidine nucleobases salvage in Escherichia coli ECOR27

Add experiment(s):


Uracil phosphoribosyltransferase (in reverse):
uracil + 5-phospho-α-D-ribose 1-diphosphate→UMP + diphosphate
(EC 2.4.2.9)
NOLOHH_13465 (upp)
Cytidylate kinase:
UMP + ATP→UDP + ADP
(EC 2.7.4.14; 2.7.4.22)
NOLOHH_02550 (pyrH)
NOLOHH_22035 (cmk)
Nucleoside-diphosphate kinase:
UDP + ATP→UTP + ADP
(EC 2.7.4.6)
NOLOHH_01075 (adk)
NOLOHH_13355 (ndk)
CTP synthase:
UTP + ATP + L-glutamine + H2O→CTP + ADP + L-glutamate + 2 H+ + phosphate
(EC 6.3.4.2)
NOLOHH_12145 (pyrG)

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information