MetaCyc Pathway: (S)-propane-1,2-diol degradation in Escherichia coli ECOR27

Add experiment(s):


Propanediol dehydratase:
(S)-propane-1,2-diol→1-propanal + H2O (EC 4.2.1.28)
NOLOHH_15990 (pduE)
NOLOHH_15995 (pduD)
NOLOHH_16000 (pduC)
1-propanal + coenzyme A + NAD+→propanoyl-CoA + NADH + H+ (EC 1.2.1.87)
NOLOHH_15945 (pduP)
Alcohol dehydrogenase (in reverse):
1-propanal + NADH + H+→propan-1-ol + NAD+ (EC 1.1.1.1)
NOLOHH_01650 (frmA)
NOLOHH_01805 (yahK)
NOLOHH_04010 (ahr)
NOLOHH_07750 (yiaY)
NOLOHH_09500 (acuI)
NOLOHH_15940
NOLOHH_19040 (adhP)
NOLOHH_20445 (adhE)
propanoyl-CoA + phosphate→propanoyl phosphate + coenzyme A (EC 2.3.1.222)
NOLOHH_14410 (pta)
NOLOHH_15965
Acetate kinase (in reverse):
propanoyl phosphate + ADP→propanoate + ATP (EC 2.7.2.1; 2.7.2.14; 2.7.2.15; 2.7.2.7)
NOLOHH_10190 (tdcD)
NOLOHH_14415 (ackA)

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information