MetaCyc Pathway: guanosine nucleotides degradation III in Escherichia coli ECOR27

Add experiment(s):


5'-nucleotidase:
GMP + H2O→guanosine + phosphate (EC 3.1.3.5)
NOLOHH_01040 (ushA)
NOLOHH_03605 (yjjG)
NOLOHH_05160 (aphA)
NOLOHH_08855 (yrfG)
NOLOHH_12295 (surE)
NOLOHH_14440 (yfbR)
Purine-nucleoside phosphorylase:
guanosine + phosphate→guanine + α-D-ribose-1-phosphate (EC 2.4.2.1; 2.4.2.15)
NOLOHH_01510 (ppnP)
NOLOHH_03545 (deoD)
NOLOHH_13920 (xapA)
Guanine deaminase:
guanine + H+ + H2O→xanthine + ammonium (EC 3.5.4.3)
NOLOHH_11555 (guaD)
Xanthine dehydrogenase:
xanthine + NAD+ + H2O→urate + NADH + H+ (EC 1.17.1.4)
NOLOHH_02020 (paoB)
NOLOHH_02025 (paoC)
NOLOHH_11630 (xdhB)
NOLOHH_11635 (xdhB)
NOLOHH_11640 (xdhA)

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information