MetaCyc Pathway: partial TCA cycle (obligate autotrophs) in Escherichia coli ECOR27

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Phosphoenolpyruvate carboxylase (in reverse):
phosphoenolpyruvate + hydrogen carbonate→oxaloacetate + phosphate (EC 4.1.1.31)
NOLOHH_05740 (ppc)
Citrate (Si)-synthase:
oxaloacetate + acetyl-CoA + H2O→citrate + coenzyme A + H+ (EC 2.3.3.1; 2.3.3.16; 2.3.3.3)
NOLOHH_23345 (gltA)
oxaloacetate[in] + an electron-transfer quinol→(S)-malate[in] + an electron-transfer quinone (EC 1.1.5.4)
NOLOHH_14800 (mqo)
Aconitate hydratase:
citrate→cis-aconitate + H2O (EC 4.2.1.3)
NOLOHH_02825 (acnB)
NOLOHH_20240 (acnA)
NOLOHH_23085 (ybhJ)
Fumarate hydratase:
(S)-malate→fumarate + H2O (EC 4.2.1.2)
NOLOHH_04790 (fumB)
NOLOHH_11260 (fumE)
NOLOHH_17815 (fumD)
NOLOHH_18150 (fumB)
NOLOHH_18155 (fumC)
Aconitate hydratase:
cis-aconitate + H2O→D-threo-isocitrate (EC 4.2.1.3)
NOLOHH_02825 (acnB)
NOLOHH_20240 (acnA)
NOLOHH_23085 (ybhJ)
Succinate dehydrogenase (ubiquinone) (in reverse):
fumarate[in] + an electron-transfer quinol→succinate[in] + an electron-transfer quinone (EC 1.3.5.1)
No genes
Isocitrate dehydrogenase (NADP(+)):
D-threo-isocitrate + NADP+→2-oxoglutarate + CO2 + NADPH (EC 1.1.1.42)
NOLOHH_20885 (icd)

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information