MetaCyc Pathway: reductive monocarboxylic acid cycle in Escherichia coli ECOR27

Pyruvate synthase (in reverse):
acetyl-CoA + CO₂ + H⁺ + 2 a reduced ferredoxin [iron-sulfur] cluster→pyruvate + coenzyme A + 2 an oxidized ferredoxin [iron-sulfur] cluster (EC 1.2.7.1)

NOLOHH_19545 (nifJ)

Formate C-acetyltransferase (in reverse):
pyruvate + coenzyme A→acetyl-CoA + formate (EC 2.3.1.54)

NOLOHH_05760 (pflC)

NOLOHH_05765 (pflD)

NOLOHH_10195 (tdcE)

NOLOHH_13015 (grcA)

NOLOHH_22070 (pflB)

NOLOHH_22075 (pflA)

NOLOHH_22485 (ybiY)

NOLOHH_22490 (ybiW)

Links:

Pathway details at MetaCyc
Fitness data for 9 genes
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All MetaCyc pathways for Escherichia coli ECOR27

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information