MetaCyc Pathway: glutaryl-CoA degradation in Escherichia coli ECOR27

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glutaryl-CoA + an oxidized electron-transfer flavoprotein + H+→(E)-glutaconyl-CoA + a reduced electron-transfer flavoprotein (EC 1.3.8.6)
No genes
(E)-glutaconyl-CoA + H+→crotonyl-CoA + CO2 (EC 1.3.8.6)
No genes
crotonyl-CoA + H2O→(S)-3-hydroxybutanoyl-CoA (EC 4.2.1.150)
NOLOHH_06375 (fadB)
NOLOHH_14195 (fadJ)
NOLOHH_19005
3-hydroxyacyl-CoA dehydrogenase:
(S)-3-hydroxybutanoyl-CoA + NAD+→acetoacetyl-CoA + NADH + H+ (EC 1.1.1.35)
NOLOHH_06375 (fadB)
NOLOHH_14195 (fadJ)
NOLOHH_19005
Acetyl-CoA C-acyltransferase (in reverse):
acetoacetyl-CoA + coenzyme A→2 acetyl-CoA (EC 2.3.1.16; 2.3.1.9)
NOLOHH_06380 (fadA)
NOLOHH_11800 (yqeF)
NOLOHH_14190 (fadI)
NOLOHH_19000
NOLOHH_19445 (paaJ)

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information