MetaCyc Pathway: L-leucine degradation III in Escherichia coli ECOR27

Add experiment(s):


Branched-chain-amino-acid transaminase:
L-leucine + 2-oxoglutarate→4-methyl-2-oxopentanoate + L-glutamate (EC 2.6.1.42; 2.6.1.6)
NOLOHH_05170 (tyrB)
NOLOHH_06780 (ilvE)
Branched-chain-2-oxoacid decarboxylase:
4-methyl-2-oxopentanoate + H+→3-methylbutanal + CO2 (EC 4.1.1.72)
No genes
Alcohol dehydrogenase (in reverse):
3-methylbutanal + NADH + H+→3-methylbutanol + NAD+ (EC 1.1.1.1)
NOLOHH_01650 (frmA)
NOLOHH_01805 (yahK)
NOLOHH_04010 (ahr)
NOLOHH_07750 (yiaY)
NOLOHH_09500 (acuI)
NOLOHH_19040 (adhP)
NOLOHH_20445 (adhE)

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information