MetaCyc Pathway: glycolysis IV in Escherichia coli ECOR27

Diphosphate--fructose-6-phosphate 1-phosphotransferase: β-D-fructofuranose 6-phosphate + diphosphate→β-D-fructofuranose 1,6-bisphosphate + H+ + phosphate (EC 2.7.1.90)

No genes

6-phosphofructokinase: β-D-fructofuranose 6-phosphate + ATP→β-D-fructofuranose 1,6-bisphosphate + ADP + H+ (EC 2.7.1.11)

NOLOHH_05965 (pfkA)

NOLOHH_17555 (pfkB)

Fructose-bisphosphate aldolase: β-D-fructofuranose 1,6-bisphosphate→glycerone phosphate + D-glyceraldehyde 3-phosphate (EC 4.1.2.13)

NOLOHH_11305 (fbaA)

NOLOHH_15445 (fbaB)

Triose-phosphate isomerase (in reverse): glycerone phosphate→D-glyceraldehyde 3-phosphate (EC 5.3.1.1)

NOLOHH_05945 (tpiA)

Glyceraldehyde-3-phosphate dehydrogenase (NADP(+)): D-glyceraldehyde 3-phosphate + NADP+ + H2O→3-phospho-D-glycerate + NADPH + 2 H+ (EC 1.2.1.9)

No genes

Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating): D-glyceraldehyde 3-phosphate + NAD+ + phosphate→3-phospho-D-glyceroyl phosphate + NADH + H+ (EC 1.2.1.12)

NOLOHH_17260 (gapA)

NOLOHH_19375 (gap)

Phosphoglycerate kinase (in reverse): 3-phospho-D-glyceroyl phosphate + ADP→3-phospho-D-glycerate + ATP (EC 2.7.2.3)

NOLOHH_11300 (pgk)

3-phospho-D-glycerate→2-phospho-D-glycerate (EC 5.4.2.12)

NOLOHH_03485

NOLOHH_07615 (gpmM)

NOLOHH_23165 (gpmA)

Phosphopyruvate hydratase: 2-phospho-D-glycerate→phosphoenolpyruvate + H2O (EC 4.2.1.11)

NOLOHH_12150 (eno)

Pyruvate kinase (in reverse): phosphoenolpyruvate + ADP + H+→pyruvate + ATP (EC 2.7.1.40)

NOLOHH_16835 (pyk)

NOLOHH_17810 (pykF)

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information