MetaCyc Pathway: superpathway of polyamine biosynthesis I in Escherichia coli ECOR27

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Arginine decarboxylase:
L-arginine + H+→agmatine + CO2 (EC 4.1.1.19)
NOLOHH_04815 (adiA)
NOLOHH_11175 (speA)
Arginase:
L-arginine + H2O→L-ornithine + urea (EC 3.5.3.1)
No genes
Lysine decarboxylase:
L-lysine + H+→cadaverine + CO2 (EC 4.1.1.18)
NOLOHH_02470 (ldcC)
NOLOHH_04740 (cadA)
Adenosylmethionine decarboxylase:
S-adenosyl-L-methionine + H+→S-adenosyl 3-(methylsulfanyl)propylamine + CO2 (EC 4.1.1.50)
NOLOHH_02815 (speD)
NOLOHH_24555 (speD)
Agmatinase:
agmatine + H2O→putrescine + urea (EC 3.5.3.11)
NOLOHH_11185 (speB)
Ornithine decarboxylase:
L-ornithine + H+→putrescine + CO2 (EC 4.1.1.17)
NOLOHH_11040 (speC)
NOLOHH_23470 (speF)
cadaverine + S-adenosyl 3-(methylsulfanyl)propylamine→aminopropylcadaverine + S-methyl-5'-thioadenosine + H+
NOLOHH_02810 (speE)
Spermidine synthase:
putrescine + S-adenosyl 3-(methylsulfanyl)propylamine→spermidine + S-methyl-5'-thioadenosine + H+ (EC 2.5.1.16)
NOLOHH_02810 (speE)
NOLOHH_24550

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information