MetaCyc Pathway: glycolate and glyoxylate degradation I in Escherichia coli ECOR27

Add experiment(s):


Glycolate dehydrogenase:
glycolate[in] + an electron-transfer quinone→glyoxylate[in] + an electron-transfer quinol (EC 1.1.99.14)
NOLOHH_10920 (glcD)
NOLOHH_10925 (glcE)
NOLOHH_10930 (glcF)
NOLOHH_17750 (ydiJ)
Tartronate-semialdehyde synthase:
2 glyoxylate + H+→(2R)-tartronate semialdehyde + CO2 (EC 4.1.1.47)
NOLOHH_00905 (gcl)
2-hydroxy-3-oxopropionate reductase (in reverse):
(2R)-tartronate semialdehyde + NAD(P)H + H+→D-glycerate + NAD(P)+ (EC 1.1.1.60)
NOLOHH_00895 (glxR)
NOLOHH_10150 (garR)
D-glycerate + ATP→2-phospho-D-glycerate + ADP + H+ (EC 2.7.1.165)
NOLOHH_00875 (glxK)
NOLOHH_10155 (garK)

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information