MetaCyc Pathway: superpathway of L-aspartate and L-asparagine biosynthesis in Escherichia coli ECOR27

Aspartate transaminase (in reverse):
oxaloacetate + L-glutamate→L-aspartate + 2-oxoglutarate (EC 2.6.1.1)

NOLOHH_03790 (yjiR)

NOLOHH_21940 (aspC)

Aspartate ammonia-lyase (in reverse):
fumarate + ammonium→L-aspartate (EC 4.3.1.1)

NOLOHH_04695 (aspA)

Aspartate--ammonia ligase:
L-aspartate + ammonium + ATP→L-asparagine + AMP + diphosphate + H⁺ (EC 6.3.1.1)

NOLOHH_06905 (asnA)

NOLOHH_23560 (asnB)

Asparaginase:
L-asparagine + H₂O→L-aspartate + ammonium (EC 3.5.1.1; 3.5.1.38; 3.5.5.4)

NOLOHH_11080 (ansB)

NOLOHH_17320 (ansA)

Links:

Pathway details at MetaCyc
Fitness data for 7 genes
Select organism:
All MetaCyc pathways for Escherichia coli ECOR27

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information