MetaCyc Pathway: fatty acid biosynthesis initiation (type II) in Dickeya dianthicola ME23

MetaCyc Pathway: fatty acid biosynthesis initiation (type II) in Dickeya dianthicola ME23

acetyl-CoA + a [carboxyl-carrier protein dimer]-N⁶-carboxybiotinyl-L-lysine→malonyl-CoA + a [biotin carboxyl-carrier-protein dimer]-N⁶-biotinyl-L-lysine (EC 2.1.3.15)

[Acyl-carrier-protein] S-malonyltransferase:
malonyl-CoA + a soluble [acyl-carrier protein]→a malonyl-[acp] + coenzyme A (EC 2.3.1.39)

Beta-ketoacyl-acyl-carrier-protein synthase III:
acetyl-CoA + a malonyl-[acp] + H⁺→an acetoacetyl-[acp] + CO₂ + coenzyme A (EC 2.3.1.180)

Links:

Pathway details at MetaCyc
Fitness data for 14 genes
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All MetaCyc pathways for Dickeya dianthicola ME23

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information