MetaCyc Pathway: gondoate biosynthesis (anaerobic) in Dickeya dianthicola 67-19

Add experiment(s):


Beta-ketoacyl-acyl-carrier-protein synthase II:
an oleoyl-[acp] + a malonyl-[acp] + H+→an (11Z)-3-oxo-icos-11-enoyl-[acp] + a soluble [acyl-carrier protein] + CO2 (EC 2.3.1.179; 2.3.1.41)
HGI48_RS07905
HGI48_RS13175
HGI48_RS13760
HGI48_RS14480
HGI48_RS21520
HGI48_RS21535
3-oxoacyl-[acyl-carrier-protein] reductase (in reverse):
an (11Z)-3-oxo-icos-11-enoyl-[acp][cytosol] + NADPH[cytosol] + H+[cytosol]→a (3R,11Z)-3-hydroxy-icos-11-enoyl-[acp][cytosol] + NADP+[cytosol] (EC 1.1.1.100)
HGI48_RS02155
HGI48_RS07910
HGI48_RS11805
HGI48_RS13185
HGI48_RS17810
HGI48_RS21530
3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase:
a (3R,11Z)-3-hydroxy-icos-11-enoyl-[acp][cytosol]→a (2E,11Z)-icosa-2,11-dienoyl-[acp][cytosol] + H2O[cytosol] (EC 4.2.1.59)
HGI48_RS05170
HGI48_RS13320
Enoyl-[acyl-carrier-protein] reductase (NADH) (in reverse):
a (2E,11Z)-icosa-2,11-dienoyl-[acp][cytosol] + NADH[cytosol] + H+[cytosol]→a gondoyl-[acp][cytosol] + NAD+[cytosol] (EC 1.3.1.9)
HGI48_RS12530
HGI48_RS13695

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information