MetaCyc Pathway: superpathway of L-tyrosine biosynthesis in Dickeya dadantii 3937

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3-deoxy-7-phosphoheptulonate synthase:
D-erythrose 4-phosphate + phosphoenolpyruvate + H2O→3-deoxy-D-arabino-heptulosonate 7-phosphate + phosphate (EC 2.5.1.54)
DDA3937_RS06560
DDA3937_RS12815
DDA3937_RS16140
3-dehydroquinate synthase:
3-deoxy-D-arabino-heptulosonate 7-phosphate→3-dehydroquinate + phosphate (EC 4.2.3.4)
DDA3937_RS19545
3-dehydroquinate dehydratase:
3-dehydroquinate→3-dehydroshikimate + H2O (EC 4.2.1.10)
DDA3937_RS01405
DDA3937_RS17000
Shikimate dehydrogenase (in reverse):
3-dehydroshikimate + NADPH + H+→shikimate + NADP+ (EC 1.1.1.25)
DDA3937_RS01720
DDA3937_RS19100
Shikimate kinase:
shikimate + ATP→shikimate 3-phosphate + ADP + H+ (EC 2.7.1.71)
DDA3937_RS05390
DDA3937_RS19550
3-phosphoshikimate 1-carboxyvinyltransferase:
shikimate 3-phosphate + phosphoenolpyruvate→5-enolpyruvoyl-shikimate 3-phosphate + phosphate (EC 2.5.1.19)
DDA3937_RS09675
Chorismate synthase:
5-enolpyruvoyl-shikimate 3-phosphate→chorismate + phosphate (EC 4.2.3.5)
DDA3937_RS14580
Chorismate mutase:
chorismate→prephenate (EC 5.4.99.5)
DDA3937_RS02280
DDA3937_RS16130
DDA3937_RS16135
Prephenate dehydrogenase:
prephenate + NAD+→3-(4-hydroxyphenyl)pyruvate + CO2 + NADH (EC 1.3.1.12)
DDA3937_RS16135
Aspartate transaminase (in reverse):
3-(4-hydroxyphenyl)pyruvate + L-glutamate→L-tyrosine + 2-oxoglutarate (EC 2.6.1.1; 2.6.1.27; 2.6.1.5; 2.6.1.57)
DDA3937_RS00500
DDA3937_RS00685
DDA3937_RS01120
DDA3937_RS02130
DDA3937_RS07555
DDA3937_RS08230
DDA3937_RS09730
DDA3937_RS12915
DDA3937_RS14050
DDA3937_RS14180
DDA3937_RS14345
DDA3937_RS17545

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information