Aspartate transaminase (in reverse):
oxaloacetate + L-glutamate→L-aspartate + 2-oxoglutarate (EC 2.6.1.1) |
| DDA3937_RS00500 |
| DDA3937_RS01120 |
| DDA3937_RS02130 |
| DDA3937_RS07555 |
| DDA3937_RS08230 |
| DDA3937_RS12915 |
| DDA3937_RS14050 |
| DDA3937_RS14180 |
| DDA3937_RS14345 |
Aspartate kinase:
L-aspartate + ATP→L-aspartyl-4-phosphate + ADP (EC 2.7.2.4) |
| DDA3937_RS00955 |
| DDA3937_RS18415 |
| DDA3937_RS19020 |
Aspartate-semialdehyde dehydrogenase (in reverse):
L-aspartyl-4-phosphate + NADPH + H+→L-aspartate 4-semialdehyde + NADP+ + phosphate (EC 1.2.1.11) |
| DDA3937_RS14470 |
| DDA3937_RS19765 |
| L-aspartate 4-semialdehyde + pyruvate→(2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + H+ + H2O (EC 4.3.3.7) |
| DDA3937_RS00405 |
| DDA3937_RS06065 |
| DDA3937_RS08035 |
| DDA3937_RS17850 |
| DDA3937_RS19685 |
Homoserine dehydrogenase (in reverse):
L-aspartate 4-semialdehyde + NAD(P)H + H+→L-homoserine + NAD(P)+ (EC 1.1.1.3) |
| DDA3937_RS00955 |
| DDA3937_RS18415 |
Homoserine kinase:
L-homoserine + ATP→O-phospho-L-homoserine + ADP + H+ (EC 2.7.1.39) |
| DDA3937_RS18410 |
Homoserine O-succinyltransferase:
L-homoserine + succinyl-CoA→O-succinyl-L-homoserine + coenzyme A (EC 2.3.1.46) |
| DDA3937_RS19065 |
| (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + NAD(P)H + H+→(S)-2,3,4,5-tetrahydrodipicolinate + NAD(P)+ + H2O (EC 1.17.1.8) |
| DDA3937_RS18315 |
Cystathionine gamma-synthase:
O-succinyl-L-homoserine + L-cysteine→L-cystathionine + H+ + succinate (EC 2.5.1.48) |
| DDA3937_RS00950 |
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase:
(S)-2,3,4,5-tetrahydrodipicolinate + succinyl-CoA + H2O→N-succinyl-2-amino-6-ketopimelate + coenzyme A (EC 2.3.1.117) |
| DDA3937_RS05100 |
Threonine synthase:
O-phospho-L-homoserine + H2O→L-threonine + phosphate (EC 4.2.3.1) |
| DDA3937_RS18405 |
Cysteine-S-conjugate beta-lyase:
L-cystathionine + H2O→L-homocysteine + ammonium + pyruvate (EC 4.4.1.13) |
| DDA3937_RS01815 |
Succinyldiaminopimelate transaminase (in reverse):
N-succinyl-2-amino-6-ketopimelate + L-glutamate→N-succinyl-L,L-2,6-diaminopimelate + 2-oxoglutarate (EC 2.6.1.17) |
| DDA3937_RS09670 |
| DDA3937_RS19450 |
5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase:
L-homocysteine + 5-methyltetrahydropteroyl tri-L-glutamate→L-methionine + tetrahydropteroyl tri-L-glutamate (EC 2.1.1.14) |
| DDA3937_RS05440 |
| DDA3937_RS11855 |
| DDA3937_RS20380 |
Methionine synthase:
L-homocysteine + a 5-methyltetrahydrofolate→L-methionine + a tetrahydrofolate (EC 2.1.1.13) |
| DDA3937_RS19040 |
Succinyl-diaminopimelate desuccinylase:
N-succinyl-L,L-2,6-diaminopimelate + H2O→L,L-diaminopimelate + succinate (EC 3.5.1.18) |
| DDA3937_RS06105 |
| DDA3937_RS16380 |
| DDA3937_RS19940 |
Diaminopimelate epimerase:
L,L-diaminopimelate→meso-diaminopimelate (EC 5.1.1.7) |
| DDA3937_RS10135 |
| DDA3937_RS19900 |
Diaminopimelate decarboxylase:
meso-diaminopimelate + H+→L-lysine + CO2 (EC 4.1.1.20) |
| DDA3937_RS07725 |
| DDA3937_RS17425 |
| DDA3937_RS20740 |
Links:
Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information