MetaCyc Pathway: mixed acid fermentation in Dickeya dadantii 3937

Add experiment(s):


Phosphoenolpyruvate carboxylase (in reverse):
phosphoenolpyruvate + hydrogen carbonate→oxaloacetate + phosphate (EC 4.1.1.31)
DDA3937_RS20360
Pyruvate kinase (in reverse):
phosphoenolpyruvate + ADP + H+→pyruvate + ATP (EC 2.7.1.40)
DDA3937_RS10125
DDA3937_RS12740
D-lactate dehydrogenase (in reverse):
pyruvate + NADH + H+→(R)-lactate + NAD+ (EC 1.1.1.28)
DDA3937_RS12295
Malate dehydrogenase (in reverse):
oxaloacetate + NADH + H+→(S)-malate + NAD+ (EC 1.1.1.37; 1.1.1.38)
DDA3937_RS02970
DDA3937_RS07530
DDA3937_RS08480
DDA3937_RS13075
Formate C-acetyltransferase (in reverse):
pyruvate + coenzyme A→acetyl-CoA + formate (EC 2.3.1.54)
DDA3937_RS09650
DDA3937_RS09655
DDA3937_RS15785
Acetaldehyde dehydrogenase (acetylating) (in reverse):
acetyl-CoA + NADH + H+→acetaldehyde + coenzyme A + NAD+ (EC 1.2.1.10)
DDA3937_RS10360
DDA3937_RS16335
Citrate (Si)-synthase:
acetyl-CoA + oxaloacetate + H2O→citrate + coenzyme A + H+ (EC 2.3.3.1; 2.3.3.16; 2.3.3.3)
DDA3937_RS06435
formate + H+→CO2 + H2
DDA3937_RS07405
DDA3937_RS07465
Fumarate hydratase:
(S)-malate→fumarate + H2O (EC 4.2.1.2)
DDA3937_RS04540
DDA3937_RS10655
Phosphate acetyltransferase:
acetyl-CoA + phosphate→acetyl phosphate + coenzyme A (EC 2.3.1.8)
DDA3937_RS14385
Acetate kinase (in reverse):
acetyl phosphate + ADP→acetate + ATP (EC 2.7.2.1; 2.7.2.15)
DDA3937_RS10145
DDA3937_RS14380
Aconitate hydratase:
citrate→cis-aconitate + H2O (EC 4.2.1.3)
DDA3937_RS12555
DDA3937_RS17885
Alcohol dehydrogenase (in reverse):
acetaldehyde + NADH + H+→ethanol + NAD+ (EC 1.1.1.1)
DDA3937_RS01315
DDA3937_RS03640
DDA3937_RS09325
DDA3937_RS10360
DDA3937_RS11900
DDA3937_RS17845
Succinate dehydrogenase (ubiquinone):
fumarate[in] + a menaquinol→succinate[in] + a menaquinone (EC 1.3.5.1)
DDA3937_RS18965
DDA3937_RS18970
DDA3937_RS18975
DDA3937_RS18980
Aconitate hydratase:
cis-aconitate + H2O→D-threo-isocitrate (EC 4.2.1.3)
DDA3937_RS12555
DDA3937_RS17885
Isocitrate dehydrogenase (NADP(+)):
D-threo-isocitrate + NADP+→CO2 + 2-oxoglutarate + NADPH (EC 1.1.1.42)
DDA3937_RS11470

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information