MetaCyc Pathway: thiamine diphosphate salvage IV (yeast) in Echinicola vietnamensis KMM 6221, DSM 17526

Add experiment(s):


Thiaminase:
thiamine + H2O→4-amino-2-methyl-5-pyrimidinemethanol + 5-(2-hydroxyethyl)-4-methylthiazole + H+ (EC 3.5.99.2)
Echvi_0214
Hydroxymethylpyrimidine kinase:
4-amino-2-methyl-5-pyrimidinemethanol + ATP→4-amino-2-methyl-5-(phosphooxymethyl)pyrimidine + ADP + H+ (EC 2.7.1.49)
Echvi_0215
Hydroxyethylthiazole kinase:
5-(2-hydroxyethyl)-4-methylthiazole + ATP→4-methyl-5-(2-phosphooxyethyl)thiazole + ADP + H+ (EC 2.7.1.50)
Echvi_0217
Phosphomethylpyrimidine kinase:
4-amino-2-methyl-5-(phosphooxymethyl)pyrimidine + ATP→4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine + ADP (EC 2.7.4.7)
Echvi_0215
Thiamine-phosphate diphosphorylase:
4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine + 4-methyl-5-(2-phosphooxyethyl)thiazole + H+→thiamine phosphate + diphosphate (EC 2.5.1.3)
Echvi_0216
Echvi_3565
Echvi_3566
thiamine phosphate + H2O→thiamine + phosphate (EC 3.1.3.100)
No genes
Thiamine diphosphokinase:
thiamine + ATP→thiamine diphosphate + AMP + H+ (EC 2.7.6.2)
Echvi_1447

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information