MetaCyc Pathway: superpathway of anaerobic sucrose degradation in Brevundimonas sp. GW460-12-10-14-LB2

Add experiment(s):


Sucrose synthase (in reverse):
sucrose + H+ + UDP→β-D-fructofuranose + UDP-α-D-glucose (EC 2.4.1.13)
No genes
Fructokinase:
β-D-fructofuranose + ATP→β-D-fructofuranose 6-phosphate + ADP + H+ (EC 2.7.1.4)
A4249_RS06845
A4249_RS15025
UTP-monosaccharide-1-phosphate uridylyltransferase (in reverse):
UDP-α-D-glucose + diphosphate→α-D-glucopyranose 1-phosphate + H+ + UTP (EC 2.7.7.64; 2.7.7.9)
A4249_RS14885
6-phosphofructokinase:
β-D-fructofuranose 6-phosphate + ATP→β-D-fructofuranose 1,6-bisphosphate + ADP + H+ (EC 2.7.1.11)
No genes
Phosphoglucomutase:
α-D-glucopyranose 1-phosphate→D-glucopyranose 6-phosphate (EC 5.4.2.2)
A4249_RS00035
A4249_RS13070
A4249_RS13095
Fructose-bisphosphate aldolase:
β-D-fructofuranose 1,6-bisphosphate→glycerone phosphate + D-glyceraldehyde 3-phosphate (EC 4.1.2.13)
A4249_RS10050
Fructose-bisphosphatase:
β-D-fructofuranose 1,6-bisphosphate + H2O→β-D-fructofuranose 6-phosphate + phosphate (EC 3.1.3.11)
A4249_RS09315
Glucose-6-phosphate isomerase:
α-D-glucose 6-phosphate→β-D-fructofuranose 6-phosphate (EC 5.3.1.9)
A4249_RS14585
Triose-phosphate isomerase (in reverse):
glycerone phosphate→D-glyceraldehyde 3-phosphate (EC 5.3.1.1)
A4249_RS06145
Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating):
D-glyceraldehyde 3-phosphate + NAD+ + phosphate→3-phospho-D-glyceroyl phosphate + NADH + H+ (EC 1.2.1.12)
A4249_RS10040
Phosphoglycerate kinase (in reverse):
3-phospho-D-glyceroyl phosphate + ADP→3-phospho-D-glycerate + ATP (EC 2.7.2.3)
A4249_RS10045
3-phospho-D-glycerate→2-phospho-D-glycerate (EC 5.4.2.12)
A4249_RS15385
3-phospho-D-glycerate→2-phospho-D-glycerate (EC 5.4.2.11)
A4249_RS15385
Phosphopyruvate hydratase:
2-phospho-D-glycerate→phosphoenolpyruvate + H2O (EC 4.2.1.11)
A4249_RS04915
Pyruvate kinase (in reverse):
phosphoenolpyruvate + ADP + H+→pyruvate + ATP (EC 2.7.1.40)
A4249_RS02440
L-lactate dehydrogenase (in reverse):
pyruvate + NADH + H+→(S)-lactate + NAD+ (EC 1.1.1.27)
No genes
Pyruvate, water dikinase:
pyruvate + ATP + H2O→phosphoenolpyruvate + AMP + 2 H+ + phosphate (EC 2.7.9.2)
No genes
Pyruvate decarboxylase:
pyruvate + H+→acetaldehyde + CO2 (EC 4.1.1.1)
No genes
Alcohol dehydrogenase (in reverse):
acetaldehyde + NADH + H+→ethanol + NAD+ (EC 1.1.1.1)
A4249_RS00315
A4249_RS00420
A4249_RS14235
A4249_RS15795

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information