MetaCyc Pathway: methylglyoxal degradation VIII in Brevundimonas sp. GW460-12-10-14-LB2

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Lactoylglutathione lyase (in reverse):
methylglyoxal + glutathione→(R)-S-lactoylglutathione
(EC 4.4.1.5)
A4249_RS03500
A4249_RS13830
Hydroxyacylglutathione hydrolase:
(R)-S-lactoylglutathione + H2O→(R)-lactate + glutathione + H+
(EC 3.1.2.6)
A4249_RS00300
A4249_RS00435
A4249_RS06505
A4249_RS16040
A4249_RS17065
D-lactate dehydrogenase (cytochrome):
(R)-lactate + 2 an oxidized c-type cytochrome→pyruvate + 2 a reduced c-type cytochrome + 2 H+
(EC 1.1.2.4)
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information