MetaCyc Pathway: 2-oxoglutarate decarboxylation to succinyl-CoA in Brevundimonas sp. GW460-12-10-14-LB2

Add experiment(s):


a [2-oxoglutarate dehydrogenase E2 protein] N6-lipoyl-L-lysine + 2-oxoglutarate + H+→a [2-oxoglutarate dehydrogenase E2 protein] N6-S-succinyldihydrolipoyl-L-lysine + CO2 (EC 1.2.1.105; 1.2.4.2)
A4249_RS14430
a [2-oxoglutarate dehydrogenase E2 protein] N6-S-succinyldihydrolipoyl-L-lysine + coenzyme A→a [2-oxoglutarate dehydrogenase E2 protein] N6-dihydrolipoyl-L-lysine + succinyl-CoA (EC 1.2.1.105; 2.3.1.61)
A4249_RS14435
a [2-oxoglutarate dehydrogenase E2 protein] N6-dihydrolipoyl-L-lysine + NAD+→a [2-oxoglutarate dehydrogenase E2 protein] N6-lipoyl-L-lysine + NADH + H+ (EC 1.2.1.105; 1.8.1.4)
A4249_RS03095
A4249_RS04950
A4249_RS12115
A4249_RS13185

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information