MetaCyc Pathway: L-valine biosynthesis in Bosea sp. OAE506

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Acetolactate synthase:
2 pyruvate + H+→(S)-2-acetolactate + CO2
(EC 2.2.1.6)
ABIE41_RS02425
ABIE41_RS12890
ABIE41_RS12905
ABIE41_RS23700
ABIE41_RS23890
Ketol-acid reductoisomerase (in reverse):
(S)-2-acetolactate + NADPH + H+→(2R)-2,3-dihydroxy-3-methylbutanoate + NADP+
(EC 1.1.1.86)
No genes
Dihydroxy-acid dehydratase:
(2R)-2,3-dihydroxy-3-methylbutanoate→3-methyl-2-oxobutanoate + H2O
(EC 4.2.1.9)
ABIE41_RS07300
ABIE41_RS10490
ABIE41_RS15690
ABIE41_RS18585
Branched-chain-amino-acid transaminase (in reverse):
3-methyl-2-oxobutanoate + L-glutamate→L-valine + 2-oxoglutarate
(EC 2.6.1.42)
ABIE41_RS11405
ABIE41_RS22510

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information