MetaCyc Pathway: heparin degradation in Phocaeicola dorei CL03T12C01

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Heparin lyase:
heparin→n 4-deoxy-2-O-sulfo-β-L-erythro-hex-4-enopyranuronosyl-(1,4)-D-N-sulfoglucosamine 6-O-sulfate (EC 4.2.2.7)
No genes
Iduronate-2-sulfatase:
4-deoxy-2-O-sulfo-β-L-erythro-hex-4-enopyranuronosyl-(1,4)-D-N-sulfoglucosamine 6-O-sulfate + H2O→4-deoxy-β-L-erythro-hex-4-enopyranuronosyl-(1,4)-D-N-sulfoglucosamine 6-O-sulfate + H+ + sulfate (EC 3.1.6.13)
ABI39_RS06355
ABI39_RS08600
Glucuronosyl-disulfoglucosamine glucuronidase:
4-deoxy-β-L-erythro-hex-4-enopyranuronosyl-(1,4)-D-N-sulfoglucosamine 6-O-sulfate + H2O→4-deoxy-L-threo-hex-4-enopyranuronate + N,6-O-disulfo-D-glucosamine (EC 3.2.1.56)
ABI39_RS08960
ABI39_RS08995
Disulfoglucosamine-6-sulfatase:
N,6-O-disulfo-D-glucosamine + H2O→N-sulfo-D-glucosamine + H+ + sulfate (EC 3.1.6.11)
No genes
N-sulfoglucosamine sulfohydrolase:
N-sulfo-D-glucosamine + H2O→D-glucosamine + sulfate (EC 3.10.1.1)
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information