MetaCyc Pathway: allopregnanolone biosynthesis in Phocaeicola dorei CL03T12C01

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Cholestenone 5-alpha-reductase (in reverse):
progesterone + NADPH + H+→5α-dihydroprogesterone + NADP+ (EC 1.3.1.22)
ABI39_RS09975
3-alpha-hydroxysteroid dehydrogenase (A-specific) (in reverse):
5α-dihydroprogesterone + NAD(P)H + H+→allopregnanolone + NAD(P)+ (EC 1.1.1.213)
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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information