MetaCyc Pathway: cis-vaccenate biosynthesis in Phocaeicola dorei CL03T12C01

Add experiment(s):


Beta-ketoacyl-acyl-carrier-protein synthase II:
a palmitoleoyl-[acp] + a malonyl-[acp] + H+→an (11Z)-3-oxooctadec-11-enoyl-[acp] + a soluble [acyl-carrier protein] + CO2
(EC 2.3.1.179)
ABI39_RS06325
ABI39_RS06480
3-oxoacyl-[acyl-carrier-protein] reductase (in reverse):
an (11Z)-3-oxooctadec-11-enoyl-[acp] + NADPH + H+→a (3R,11Z)-3-hydroxyoctadec-11-enoyl-[acp] + NADP+
(EC 1.1.1.100)
ABI39_RS02135
ABI39_RS03255
ABI39_RS03550
ABI39_RS06475
ABI39_RS06545
ABI39_RS11075
ABI39_RS11985
ABI39_RS16765
ABI39_RS19260
ABI39_RS19330
3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase:
a (3R,11Z)-3-hydroxyoctadec-11-enoyl-[acp]→a (2E,11Z)-octadeca-2,11-dienoyl-[acp] + H2O
(EC 4.2.1.59)
ABI39_RS00505
Enoyl-[acyl-carrier-protein] reductase (NADH) (in reverse):
a (2E,11Z)-octadeca-2,11-dienoyl-[acp] + NADH + H+→a cis-vaccenoyl-[acp] + NAD+
(EC 1.3.1.9)
ABI39_RS10085
ABI39_RS14315
Oleoyl-[acyl-carrier-protein] hydrolase:
a cis-vaccenoyl-[acp] + H2Ocis-vaccenate + a soluble [acyl-carrier protein] + H+
(EC 3.1.2.14)
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information