MetaCyc Pathway: 2-carboxy-1,4-naphthoquinol biosynthesis in Phocaeicola dorei CL03T12C01

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Isochorismate synthase:
chorismate→isochorismate
(EC 5.4.4.2)
ABI39_RS12145
synthase:
isochorismate + 2-oxoglutarate + H+→(1R,2S,5S,6S)-2-succinyl-5-enolpyruvyl-6-hydroxycyclohex-3-ene-1-carboxylate + CO2
(EC 2.2.1.9)
ABI39_RS11070
ABI39_RS11995
ABI39_RS12140
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase:
(1R,2S,5S,6S)-2-succinyl-5-enolpyruvyl-6-hydroxycyclohex-3-ene-1-carboxylate→(1R,6R)-6-hydroxy-2-succinylcyclohexa-2,4-diene-1-carboxylate + pyruvate
(EC 4.2.99.20)
No genes
o-succinylbenzoate synthase:
(1R,6R)-6-hydroxy-2-succinylcyclohexa-2,4-diene-1-carboxylate→2-succinylbenzoate + H2O
(EC 4.2.1.113)
ABI39_RS12125
o-succinylbenzoate--CoA ligase:
2-succinylbenzoate + ATP + coenzyme A→4-(2'-carboxyphenyl)-4-oxobutyryl-CoA + AMP + diphosphate
(EC 6.2.1.26)
ABI39_RS07795
ABI39_RS12120
Naphthoate synthase:
4-(2'-carboxyphenyl)-4-oxobutyryl-CoA + H+→1,4-dihydroxy-2-naphthoyl-CoA + H2O
(EC 4.1.3.36)
ABI39_RS12135
1,4-dihydroxy-2-naphthoyl-CoA + H2O→1,4-dihydroxy-2-naphthoate + coenzyme A + H+ (EC 3.1.2.28)
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information