MetaCyc Pathway: superpathway of phospholipid biosynthesis III (E. coli) in Phocaeicola dorei CL03T12C01

Add experiment(s):


Glycerol-3-phosphate dehydrogenase (NAD(P)(+)) (in reverse):
glycerone phosphate + NAD(P)H + H+sn-glycerol 3-phosphate + NAD(P)+
(EC 1.1.1.94)
ABI39_RS21145
Glycerol-3-phosphate O-acyltransferase:
sn-glycerol 3-phosphate + an acyl-[acyl-carrier protein]→a 2-lysophosphatidate + a soluble [acyl-carrier protein]
(EC 2.3.1.15)
No genes
Glycerol-3-phosphate O-acyltransferase:
sn-glycerol 3-phosphate + an acyl-CoA→a 2-lysophosphatidate + coenzyme A
(EC 2.3.1.15)
No genes
1-acylglycerol-3-phosphate O-acyltransferase:
a 2-lysophosphatidate + an acyl-[acyl-carrier protein]→a phosphatidate + a soluble [acyl-carrier protein]
(EC 2.3.1.51)
ABI39_RS06425
ABI39_RS11350
1-acylglycerol-3-phosphate O-acyltransferase:
a 2-lysophosphatidate + an acyl-CoA→a phosphatidate + coenzyme A
(EC 2.3.1.51)
ABI39_RS06425
ABI39_RS11350
Phosphatidate cytidylyltransferase:
a phosphatidate + CTP + H+→a CDP-diacylglycerol + diphosphate
(EC 2.7.7.41)
ABI39_RS09750
CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase:
a CDP-diacylglycerol + sn-glycerol 3-phosphate→a phosphatidylglycerophosphate + CMP + H+
(EC 2.7.8.5)
No genes
CDP-diacylglycerol--serine O-phosphatidyltransferase:
a CDP-diacylglycerol + L-serine→a phosphatidylserine + CMP + H+
(EC 2.7.8.8)
ABI39_RS09525
Phosphatidylglycerophosphatase:
a phosphatidylglycerophosphate + H2O→a phosphatidylglycerol + phosphate
(EC 3.1.3.27)
No genes
Phosphatidylserine decarboxylase:
a phosphatidylserine + H+→a phosphatidylethanolamine + CO2
(EC 4.1.1.65)
ABI39_RS09530
2 a phosphatidylglycerol→a cardiolipin + glycerol (EC 2.7.8.41)
No genes
a phosphatidylethanolamine + a phosphatidylglycerol→a cardiolipin + ethanolamine (EC 2.7.8.41)
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information