MetaCyc Pathway: TCA cycle VIII (Chlamydia) in Escherichia coli BL21

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2-oxoglutarate + coenzyme A + NAD+→succinyl-CoA + CO2 + NADH (EC 1.2.1.105)
ECD_00115
Succinate--CoA ligase (ADP-forming) (in reverse):
succinyl-CoA + ADP + phosphate→succinate + ATP + coenzyme A
(EC 6.2.1.5)
ECD_00687
ECD_00688
Succinate dehydrogenase (ubiquinone):
succinate[in] + an electron-transfer quinone→fumarate[in] + an electron-transfer quinol
(EC 1.3.5.1)
No genes
Fumarate hydratase (in reverse):
fumarate + H2O→(S)-malate
(EC 4.2.1.2)
ECD_01580
ECD_01581
ECD_01644
ECD_02760
ECD_03993
Malate dehydrogenase:
(S)-malate + NAD+→oxaloacetate + NADH + H+
(EC 1.1.1.37; 1.1.1.38)
ECD_00768
ECD_01437
ECD_03096
Aspartate transaminase (in reverse):
oxaloacetate + L-glutamate→2-oxoglutarate + L-aspartate
(EC 2.6.1.1)
ECD_00932

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information