MetaCyc Pathway: superpathway of pyrimidine deoxyribonucleosides degradation in Escherichia coli BL21

Add experiment(s):


Cytidine deaminase:
2'-deoxycytidine + H+ + H2O→2'-deoxyuridine + ammonium (EC 3.5.4.5)
ECD_02072
Pyrimidine-nucleoside phosphorylase:
thymidine + phosphate→2-deoxy-α-D-ribose 1-phosphate + thymine (EC 2.4.2.2; 2.4.2.4)
ECD_00338
ECD_04258
Pyrimidine-nucleoside phosphorylase:
2'-deoxyuridine + phosphate→2-deoxy-α-D-ribose 1-phosphate + uracil (EC 2.4.2.2; 2.4.2.3)
ECD_03718
ECD_04258
ECD_04260
Phosphopentomutase:
2-deoxy-α-D-ribose 1-phosphate→2-deoxy-D-ribose 5-phosphate (EC 5.4.2.7)
ECD_03232
ECD_04259
Deoxyribose-phosphate aldolase:
2-deoxy-D-ribose 5-phosphate→acetaldehyde + D-glyceraldehyde 3-phosphate (EC 4.1.2.4)
ECD_04257
Acetaldehyde dehydrogenase (acetylating):
acetaldehyde + coenzyme A + NAD+→acetyl-CoA + NADH + H+ (EC 1.2.1.10)
ECD_00305
ECD_01215
ECD_02346

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information