MetaCyc Pathway: pyruvate fermentation to ethanol III in Escherichia coli BL21

Pyruvate synthase:
pyruvate + coenzyme A + 2 an oxidized ferredoxin [iron-sulfur] cluster→acetyl-CoA + CO₂ + H⁺ + 2 a reduced ferredoxin [iron-sulfur] cluster (EC 1.2.7.1)

ECD_01349

Acetaldehyde dehydrogenase (acetylating) (in reverse):
acetyl-CoA + NADH + H⁺→acetaldehyde + coenzyme A + NAD⁺ (EC 1.2.1.10)

ECD_00305

ECD_01215

ECD_02346

Alcohol dehydrogenase (in reverse):
acetaldehyde + NADH + H⁺→ethanol + NAD⁺ (EC 1.1.1.1)

Links:

Pathway details at MetaCyc
Fitness data for 10 genes
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All MetaCyc pathways for Escherichia coli BL21

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information