MetaCyc Pathway: 2-allylmalonyl-CoA biosynthesis in Azospirillum sp. SherDot2

Add experiment(s):


propanoyl-CoA + TcsB polyketide synthase→propanoyl-[TcsB polyketide synthase] + coenzyme A
No genes
malonyl-CoA + TcsA polyketide synthase→malonyl-[TcsA polyketide synthase] + coenzyme A
No genes
malonyl-[TcsA polyketide synthase] + propanoyl-[TcsB polyketide synthase] + H+→3-oxopentanoyl-[TcsA polyketide synthase] + CO2 + TcsB polyketide synthase
No genes
3-oxoacyl-[acyl-carrier-protein] reductase (in reverse):
3-oxopentanoyl-[TcsA polyketide synthase] + NADPH + H+→(3R)-3-hydroxypentanoyl-[TcsA polyketide synthase] + NADP+ (EC 1.1.1.100)
MPMX19_00938
MPMX19_01147
MPMX19_01299
MPMX19_02782
MPMX19_02788
MPMX19_02816
MPMX19_02999
MPMX19_03000
MPMX19_03169
MPMX19_03216
MPMX19_03281
MPMX19_03548
MPMX19_03667
MPMX19_03857
MPMX19_03871
MPMX19_03919
MPMX19_04140
MPMX19_04205
MPMX19_04522
MPMX19_04767
MPMX19_04816
MPMX19_04993
MPMX19_05226
MPMX19_05469
MPMX19_05644
MPMX19_06770
MPMX19_06773
MPMX19_06974
MPMX19_06989
3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase:
(3R)-3-hydroxypentanoyl-[TcsA polyketide synthase]→(2E)-pent-2-enoyl-[TcsA polyketide synthase] + H2O (EC 4.2.1.59)
MPMX19_00999
(2E)-pent-2-enoyl-[TcsA polyketide synthase] + CO2 + NADPH→2-carboxypentanoyl-[TcsA polyketide synthase] + NADP+
No genes
2-carboxypentanoyl-[TcsA polyketide synthase] + FAD + H+→2-allylmalonyl-[TcsA polyketide synthase] + FADH2
No genes
2-allylmalonyl-[TcsA polyketide synthase] + coenzyme A→2-allylmalonyl-CoA + TcsA polyketide synthase
No genes

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information