MetaCyc Pathway: crotonate fermentation (to acetate and cyclohexane carboxylate) in Azospirillum sp. SherDot2

Add experiment(s):


acetyl-CoA + crotonate→acetate + crotonyl-CoA
No genes
crotonyl-CoA + CO2→(E)-glutaconyl-CoA + H+ (EC 1.3.8.6)
No genes
crotonyl-CoA + H2O→(S)-3-hydroxybutanoyl-CoA (EC 4.2.1.150)
MPMX19_01506
MPMX19_01519
MPMX19_02329
MPMX19_02766
MPMX19_03391
MPMX19_03907
MPMX19_04243
MPMX19_04526
MPMX19_04613
MPMX19_05225
MPMX19_05231
MPMX19_05776
MPMX19_06872
MPMX19_06875
MPMX19_06916
MPMX19_06938
MPMX19_06944
(E)-glutaconyl-CoA + a reduced electron-transfer flavoprotein→glutaryl-CoA + an oxidized electron-transfer flavoprotein + H+ (EC 1.3.8.6)
No genes
3-hydroxyacyl-CoA dehydrogenase:
(S)-3-hydroxybutanoyl-CoA + NAD+→acetoacetyl-CoA + NADH + H+ (EC 1.1.1.35)
MPMX19_00640
MPMX19_03296
MPMX19_04900
MPMX19_05225
MPMX19_05943
MPMX19_06153
MPMX19_06944
Acetyl-CoA C-acyltransferase (in reverse):
acetoacetyl-CoA + coenzyme A→2 acetyl-CoA (EC 2.3.1.16; 2.3.1.9)
MPMX19_01912
MPMX19_03465
MPMX19_03936
MPMX19_04608
MPMX19_04667
MPMX19_04901
MPMX19_05089
MPMX19_05232
MPMX19_05779
MPMX19_05859
MPMX19_06343
MPMX19_06951
acetyl-CoA + glutaryl-CoA→3-oxopimeloyl-CoA + coenzyme A
MPMX19_04608
3-hydroxypimeloyl-CoA dehydrogenase (in reverse):
3-oxopimeloyl-CoA + NADH + H+→3-hydroxypimeloyl-CoA + NAD+ (EC 1.1.1.259)
No genes
Acetate--CoA ligase (ADP-forming) (in reverse):
acetyl-CoA + ADP + phosphate→acetate + ATP + coenzyme A (EC 6.2.1.13)
No genes
3-hydroxypimeloyl-CoA + H+→2-hydroxy-6-oxocyclohexane-1-carbonyl-CoA + H2O (EC 3.7.1.21)
No genes
2-hydroxy-6-oxocyclohexane-1-carbonyl-CoA→6-oxocyclohex-1-ene-1-carbonyl-CoA + H2O (EC 3.7.1.21)
No genes
6-oxocyclohex-1-ene-1-carbonyl-CoA + NADH + H+→6-hydroxycyclohex-1-ene-1-carbonyl-CoA + NAD+ (EC 1.1.1.368)
No genes
Cyclohexa-1,5-dienecarbonyl-CoA hydratase:
6-hydroxycyclohex-1-ene-1-carbonyl-CoA→cyclohex-1,5-diene-1-carbonyl-CoA + H2O (EC 4.2.1.100)
No genes
cyclohex-1,5-diene-1-carbonyl-CoA + a reduced electron-transfer flavoprotein→cyclohex-1-ene-1-carbonyl-CoA + an oxidized electron-transfer flavoprotein + H+ (EC 1.3.8.10)
MPMX19_06941
cyclohex-1-ene-1-carbonyl-CoA + a reduced electron-transfer flavoprotein→cyclohexane-1-carbonyl-CoA + an oxidized electron-transfer flavoprotein + H+ (EC 1.3.8.11)
No genes
cyclohexane-1-carbonyl-CoA + H2O→cyclohexane-1-carboxylate + coenzyme A + H+
No genes

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information