MetaCyc Pathway: L-histidine degradation II in Azospirillum sp. SherDot2

Histidine ammonia-lyase:
L-histidine→urocanate + ammonium (EC 4.3.1.3)

MPMX19_04940

Urocanate hydratase (in reverse):
urocanate + H₂O→4-imidazolone-5-propanoate (EC 4.2.1.49)

MPMX19_04936

Imidazolonepropionase:
4-imidazolone-5-propanoate + H₂O→N-formimino-L-glutamate (EC 3.5.2.7)

MPMX19_04938

Formimidoylglutamate deiminase:
N-formimino-L-glutamate + H₂O→N-formyl-L-glutamate + ammonium (EC 3.5.3.13)

MPMX19_03398

MPMX19_04939

N-formylglutamate deformylase:
N-formyl-L-glutamate + H₂O→L-glutamate + formate (EC 3.5.1.68)

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Pathway details at MetaCyc
Fitness data for 9 genes
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All MetaCyc pathways for Azospirillum sp. SherDot2

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information