MetaCyc Pathway: folate polyglutamylation in Azospirillum sp. SherDot2

Add experiment(s):


Tetrahydrofolate synthase:
a tetrahydrofolate + ATP + L-glutamate→a tetrahydrofolate + ADP + phosphate (EC 6.3.2.17)
MPMX19_02739
Formate--tetrahydrofolate ligase:
a tetrahydrofolate + ATP + formate→an N10-formyltetrahydrofolate + ADP + phosphate (EC 6.3.4.3)
No genes
Glycine hydroxymethyltransferase:
a tetrahydrofolate + L-serine→a 5,10-methylenetetrahydrofolate + glycine + H2O (EC 2.1.2.1)
MPMX19_00727
MPMX19_03072
MPMX19_04704
Tetrahydrofolate synthase:
an N10-formyltetrahydrofolate + ATP + L-glutamate→an N10-formyltetrahydrofolate + ADP + phosphate (EC 6.3.2.17)
MPMX19_02739
Tetrahydrofolate synthase:
a 5,10-methylenetetrahydrofolate + ATP + L-glutamate→a 5,10-methylenetetrahydrofolate + ADP + phosphate (EC 6.3.2.17)
MPMX19_02739

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information