MetaCyc Pathway: L-lysine fermentation to acetate and butanoate in Azospirillum sp. SherDot2

Add experiment(s):


Lysine 2,3-aminomutase:
L-lysine→L-β-lysine (EC 5.4.3.2)
MPMX19_00061
Beta-lysine 5,6-aminomutase:
L-β-lysine→(3S,5S)-3,5-diaminohexanoate (EC 5.4.3.3)
No genes
L-erythro-3,5-diaminohexanoate dehydrogenase:
(3S,5S)-3,5-diaminohexanoate + NAD+ + H2O→(S)-5-amino-3-oxohexanoate + ammonium + NADH + H+ (EC 1.4.1.11)
No genes
(S)-5-amino-3-oxohexanoate + acetyl-CoA→acetoacetate + (S)-3-aminobutanoyl-CoA (EC 2.3.1.247)
No genes
3-aminobutyryl-CoA ammonia-lyase:
(S)-3-aminobutanoyl-CoA→crotonyl-CoA + ammonium (EC 4.3.1.14)
No genes
crotonyl-CoA[cytosol] + 2 NADH[cytosol] + 2 an oxidized ferredoxin [iron-sulfur] cluster[cytosol]→butanoyl-CoA[cytosol] + 2 NAD+[cytosol] + 2 a reduced ferredoxin [iron-sulfur] cluster[cytosol] (EC 1.3.1.109)
No genes
Butyrate--acetoacetate CoA-transferase:
acetoacetate + butanoyl-CoA→acetoacetyl-CoA + butanoate (EC 2.8.3.9)
MPMX19_03463
MPMX19_05364
Acetyl-CoA C-acyltransferase (in reverse):
acetoacetyl-CoA + coenzyme A→2 acetyl-CoA (EC 2.3.1.16; 2.3.1.9)
MPMX19_01912
MPMX19_03465
MPMX19_03936
MPMX19_04608
MPMX19_04667
MPMX19_04901
MPMX19_05089
MPMX19_05232
MPMX19_05779
MPMX19_05859
MPMX19_06343
MPMX19_06951
Phosphate acetyltransferase:
acetyl-CoA + phosphate→acetyl phosphate + coenzyme A (EC 2.3.1.8)
MPMX19_00515
MPMX19_02846
Acetate kinase (in reverse):
acetyl phosphate + ADP→acetate + ATP (EC 2.7.2.1; 2.7.2.15)
MPMX19_00516
MPMX19_02847

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information