MetaCyc Pathway: superpathway of heme b biosynthesis from uroporphyrinogen-III in Alteromonas macleodii MIT1002

Add experiment(s):


Uroporphyrinogen decarboxylase:
uroporphyrinogen-III + 4 H+→coproporphyrinogen III + 4 CO2 (EC 4.1.1.37)
MIT1002_03796
coproporphyrinogen III + 2 S-adenosyl-L-methionine→protoporphyrinogen IX + 2 CO2 + 2 5'-deoxyadenosine + 2 L-methionine (EC 1.3.98.3)
MIT1002_02323
Coproporphyrinogen oxidase:
coproporphyrinogen III + dioxygen + 2 H+→protoporphyrinogen IX + 2 CO2 + 2 H2O (EC 1.3.3.3)
MIT1002_00026
protoporphyrinogen IX[in] + 3 a ubiquinone→protoporphyrin IX[in] + 3 a ubiquinol (EC 1.3.5.3)
No genes
protoporphyrinogen IX[in] + 3 a menaquinone→protoporphyrin IX[in] + 3 a menaquinol (EC 1.3.5.3)
No genes
protoporphyrin IX + Fe2+→protoheme + 2 H+ (EC 4.98.1.1)
MIT1002_03783

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information