MetaCyc Pathway: 8-amino-7-oxononanoate biosynthesis IV in Agrobacterium fabrum C58

glutaryl-CoA + a malonyl-[acp] + H+→a 3-oxopimeloyl-[acp] + CO2 + coenzyme A

Atu4001

3-oxoacyl-[acyl-carrier-protein] reductase (in reverse): a 3-oxopimeloyl-[acp] + NADPH + H+→a (3R)-3-hydroxypimeloyl-[acp] + NADP+ (EC 1.1.1.100)

Atu0705

Atu0990

Atu1095

Atu1255

Atu1338

Atu2042

Atu3051

Atu3074

Atu3333

Atu3531

Atu3813

Atu4220

Atu4325

Atu4595

Atu4821

Atu4877

Atu5122

Atu5214

Atu5250

Atu5438

Atu5465

3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase: a (3R)-3-hydroxypimeloyl-[acp]→a 2-enoyl-pimeloyl-[acp] + H2O (EC 4.2.1.59)

Atu0151

Atu1383

Atu1599

Enoyl-[acyl-carrier-protein] reductase (NADH) (in reverse): a 2-enoyl-pimeloyl-[acp] + NADH + H+→a pimeloyl-[acp] + NAD+ (EC 1.3.1.9)

Atu0149

Atu0757

8-amino-7-oxononanoate synthase: a pimeloyl-[acp] + L-alanine + H+→(8S)-8-amino-7-oxononanoate + a soluble [acyl-carrier protein] + CO2 (EC 2.3.1.47)

Atu3998

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information