Aspartate kinase:
L-aspartate + ATP→L-aspartyl-4-phosphate + ADP (EC 2.7.2.4) |
| Atu4172 |
Aspartate-semialdehyde dehydrogenase (in reverse):
L-aspartyl-4-phosphate + NADPH + H+→L-aspartate 4-semialdehyde + NADP+ + phosphate (EC 1.2.1.11) |
| Atu2490 |
| L-aspartate 4-semialdehyde + pyruvate→(2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + H+ + H2O (EC 4.3.3.7) |
| Atu0899 |
| Atu1024 |
| Atu2503 |
| Atu3960 |
| Atu4189 |
| Atu5067 |
| Atu5394 |
| Atu5398 |
| Atu5457 |
| (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + NAD(P)H + H+→(S)-2,3,4,5-tetrahydrodipicolinate + NAD(P)+ + H2O (EC 1.17.1.8) |
| Atu0183 |
Tetrahydrodipicolinate N-acetyltransferase:
(S)-2,3,4,5-tetrahydrodipicolinate + acetyl-CoA + H2O→L-2-acetamido-6-oxoheptanedioate + coenzyme A (EC 2.3.1.89) |
| No genes |
| L-2-acetamido-6-oxoheptanedioate + L-glutamate→N-acetyl-L,L-2,6-diaminopimelate + 2-oxoglutarate |
| No genes |
N-acetyldiaminopimelate deacetylase:
N-acetyl-L,L-2,6-diaminopimelate + H2O→L,L-diaminopimelate + acetate (EC 3.5.1.47) |
| Atu2732 |
| Atu3635 |
| Atu4444 |
Diaminopimelate epimerase:
L,L-diaminopimelate→meso-diaminopimelate (EC 5.1.1.7) |
| Atu0600 |
| Atu2695 |
| Atu4835 |
Diaminopimelate decarboxylase:
meso-diaminopimelate + H+→L-lysine + CO2 (EC 4.1.1.20) |
| Atu1673 |
| Atu3601 |
Links:
Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information