MetaCyc Pathway: 2-methyl-branched fatty acid β-oxidation in Acinetobacter radioresistens SK82

Add experiment(s):


Butyrate--CoA ligase:
a short-chain 2-methyl-branched fatty acid + ATP + coenzyme A→a short-chain 2-methyl fatty acyl-CoA + AMP + diphosphate (EC 6.2.1.2)
No genes
a long-chain 2-methyl fatty acyl-CoA + an oxidized electron-transfer flavoprotein + H+→a long-chain (2E)-2-methyl-2-enoyl-CoA + a reduced electron-transfer flavoprotein (EC 1.3.8.8)
MPMX26_02023
MPMX26_02693
Butyrate--CoA ligase:
a medium-chain 2-methyl-branched fatty acid + ATP + coenzyme A→a medium-chain 2-methyl fatty acyl-CoA + AMP + diphosphate (EC 6.2.1.2)
No genes
a short-chain 2-methyl fatty acyl-CoA + an oxidized electron-transfer flavoprotein + H+→a short-chain (2E)-2-methyl-2-enoyl-CoA + a reduced electron-transfer flavoprotein (EC 1.3.8.5)
No genes
a medium-chain 2-methyl fatty acyl-CoA + an oxidized electron-transfer flavoprotein + H+→a medium-chain (2E)-2-methyl-2-enoyl-CoA + a reduced electron-transfer flavoprotein (EC 1.3.8.7)
MPMX26_00339
MPMX26_02023
MPMX26_02628
MPMX26_02629
MPMX26_02693
MPMX26_02750
MPMX26_03055
Enoyl-CoA hydratase (in reverse):
a long-chain (2E)-2-methyl-2-enoyl-CoA + H2O→a long-chain (3S)-3-hydroxy-2-methylacyl-CoA (EC 4.2.1.17)
MPMX26_00226
MPMX26_00534
MPMX26_00610
MPMX26_01232
MPMX26_01501
MPMX26_01545
MPMX26_01546
MPMX26_01555
MPMX26_02179
MPMX26_03058
Enoyl-CoA hydratase (in reverse):
a short-chain (2E)-2-methyl-2-enoyl-CoA + H2O→a short-chain (3S)-3-hydroxy-2-methylacyl-CoA (EC 4.2.1.17)
MPMX26_00226
MPMX26_00534
MPMX26_00610
MPMX26_01232
MPMX26_01501
MPMX26_01545
MPMX26_01546
MPMX26_01555
MPMX26_02179
MPMX26_03058
Enoyl-CoA hydratase (in reverse):
a medium-chain (2E)-2-methyl-2-enoyl-CoA + H2O→a medium-chain (3S)-3-hydroxy-2-methylacyl-CoA (EC 4.2.1.17)
MPMX26_00226
MPMX26_00534
MPMX26_00610
MPMX26_01232
MPMX26_01501
MPMX26_01545
MPMX26_01546
MPMX26_01555
MPMX26_02179
MPMX26_03058
3-hydroxyacyl-CoA dehydrogenase:
a long-chain (3S)-3-hydroxy-2-methylacyl-CoA + NAD+→a long-chain 2-methyl-3-oxoacyl-CoA + NADH + H+ (EC 1.1.1.35)
MPMX26_00226
MPMX26_00610
MPMX26_01177
MPMX26_03059
3-hydroxy-2-methylbutyryl-CoA dehydrogenase:
a short-chain (3S)-3-hydroxy-2-methylacyl-CoA + NAD+→a short-chain 2-methyl-3-oxoacyl-CoA + NADH + H+ (EC 1.1.1.178)
No genes
3-hydroxyacyl-CoA dehydrogenase:
a medium-chain (3S)-3-hydroxy-2-methylacyl-CoA + NAD+→a medium-chain 2-methyl-3-oxoacyl-CoA + NADH + H+ (EC 1.1.1.35)
MPMX26_00226
MPMX26_00610
MPMX26_01177
MPMX26_03059
Acetyl-CoA C-acyltransferase (in reverse):
a long-chain 2-methyl-3-oxoacyl-CoA + coenzyme A→a long-chain 2-methyl fatty acyl-CoA + propanoyl-CoA (EC 2.3.1.16)
MPMX26_00225
MPMX26_00611
MPMX26_00837
MPMX26_01592
MPMX26_01701
MPMX26_01750
MPMX26_02383
MPMX26_02495
Acetyl-CoA C-acyltransferase (in reverse):
a short-chain 2-methyl-3-oxoacyl-CoA + coenzyme A→a short-chain 2-methyl fatty acyl-CoA + propanoyl-CoA (EC 2.3.1.16)
MPMX26_00225
MPMX26_00611
MPMX26_00837
MPMX26_01592
MPMX26_01701
MPMX26_01750
MPMX26_02383
MPMX26_02495
Acetyl-CoA C-acyltransferase (in reverse):
a medium-chain 2-methyl-3-oxoacyl-CoA + coenzyme A→a medium-chain 2-methyl fatty acyl-CoA + propanoyl-CoA (EC 2.3.1.16)
MPMX26_00225
MPMX26_00611
MPMX26_00837
MPMX26_01592
MPMX26_01701
MPMX26_01750
MPMX26_02383
MPMX26_02495

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information