MetaCyc Pathway: superpathway of glyoxylate cycle and fatty acid degradation in Acinetobacter baumannii LAC-4

Add experiment(s):


a 2,3,4-saturated fatty acid + ATP + coenzyme A→a 2,3,4-saturated fatty acyl CoA + AMP + diphosphate
No genes
Acyl-CoA oxidase:
a 2,3,4-saturated fatty acyl CoA + dioxygen→a (2E)-2-enoyl-CoA + hydrogen peroxide
(EC 1.3.3.6)
No genes
Enoyl-CoA hydratase (in reverse):
a (2E)-2-enoyl-CoA + H2O→a 2,3,4-saturated (3S)-3-hydroxyacyl-CoA
(EC 4.2.1.17)
RR41_RS03215
RR41_RS04720
RR41_RS08640
RR41_RS09825
RR41_RS10875
RR41_RS10880
RR41_RS11015
RR41_RS11050
RR41_RS12115
RR41_RS16105
RR41_RS17450
RR41_RS18320
RR41_RS18325
3-hydroxyacyl-CoA dehydrogenase:
a 2,3,4-saturated (3S)-3-hydroxyacyl-CoA + NAD+→a 2,3,4-saturated 3-oxoacyl-CoA + NADH + H+
(EC 1.1.1.35)
RR41_RS03215
RR41_RS06885
RR41_RS10510
RR41_RS11040
RR41_RS17450
Acetyl-CoA C-acyltransferase (in reverse):
a 2,3,4-saturated 3-oxoacyl-CoA + coenzyme A→a 2,3,4-saturated fatty acyl CoA + acetyl-CoA
(EC 2.3.1.16)
RR41_RS03220
RR41_RS03265
RR41_RS07405
RR41_RS10890
RR41_RS11035
RR41_RS12900
RR41_RS13605
RR41_RS13800
RR41_RS17455
Citrate (Si)-synthase:
acetyl-CoA + oxaloacetate + H2O→citrate + coenzyme A + H+
(EC 2.3.3.1; 2.3.3.16; 2.3.3.3)
RR41_RS04020
Aconitate hydratase:
citrate→cis-aconitate + H2O
(EC 4.2.1.3)
RR41_RS06995
RR41_RS16180
RR41_RS18475
Aconitate hydratase:
cis-aconitate + H2O→D-threo-isocitrate
(EC 4.2.1.3)
RR41_RS06995
RR41_RS16180
RR41_RS18475
Isocitrate lyase:
D-threo-isocitrate→glyoxylate + succinate
(EC 4.1.3.1)
RR41_RS08965
Malate synthase:
acetyl-CoA + glyoxylate + H2O→(S)-malate + coenzyme A + H+
(EC 2.3.3.9)
RR41_RS12185
Succinate dehydrogenase (ubiquinone):
succinate[in] + an electron-transfer quinone→fumarate[in] + an electron-transfer quinol
(EC 1.3.5.1)
RR41_RS04025
RR41_RS04030
RR41_RS04040
Fumarate hydratase (in reverse):
fumarate + H2O→(S)-malate
(EC 4.2.1.2)
RR41_RS07970
RR41_RS16545
Malate dehydrogenase:
(S)-malate + NAD+→oxaloacetate + NADH + H+
(EC 1.1.1.37; 1.1.1.38)
RR41_RS02465
RR41_RS18215
Phosphoenolpyruvate carboxykinase (ATP):
oxaloacetate + ATP→phosphoenolpyruvate + ADP + CO2
(EC 4.1.1.49)
No genes

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information