MetaCyc Pathway: incomplete reductive TCA cycle in Dickeya dadantii 3937

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Reactions and Genes Upstate
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Pyruvate synthase (in reverse):
acetyl-CoA + CO2 + H+ + 2 a reduced ferredoxin [iron-sulfur] cluster→pyruvate + coenzyme A + 2 an oxidized ferredoxin [iron-sulfur] cluster (EC 1.2.7.1)
DDA3937_RS03575 -0.7
DDA3937_RS18930 +0.1
Pyruvate carboxylase:
pyruvate + ATP + hydrogen carbonate→oxaloacetate + ADP + H+ + phosphate (EC 6.4.1.1)
No genes
Malate dehydrogenase (in reverse):
oxaloacetate + NADH + H+→(S)-malate + NAD+ (EC 1.1.1.37; 1.1.1.38)
DDA3937_RS02970 -0.4
DDA3937_RS07530 +0.3
DDA3937_RS08480 -0.8
DDA3937_RS13075 +0.5
Fumarate hydratase:
(S)-malate→fumarate + H2O (EC 4.2.1.2)
DDA3937_RS04540 -0.3
DDA3937_RS10655 +0.2
Succinate dehydrogenase (ubiquinone):
fumarate[in] + a menaquinol→succinate[in] + a menaquinone (EC 1.3.5.1)
DDA3937_RS18965 -1.3
DDA3937_RS18970 -0.9
DDA3937_RS18975 -0.7
DDA3937_RS18980 -2.5
Succinate--CoA ligase (ADP-forming):
succinate + ATP + coenzyme A→succinyl-CoA + ADP + phosphate (EC 6.2.1.5)
DDA3937_RS06470 N.D.
DDA3937_RS06475 -1.3
2-oxoglutarate synthase (in reverse):
succinyl-CoA + CO2 + H+ + 2 a reduced ferredoxin [iron-sulfur] cluster→2-oxoglutarate + coenzyme A + 2 an oxidized ferredoxin [iron-sulfur] cluster (EC 1.2.7.3)
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information