MetaCyc Pathway: mixed acid fermentation in Dickeya dadantii 3937

Reactions and Genes	Upstate
Phosphoenolpyruvate carboxylase (in reverse): phosphoenolpyruvate + hydrogen carbonate→oxaloacetate + phosphate (EC 4.1.1.31)
DDA3937_RS20360	-0.0
Pyruvate kinase (in reverse): phosphoenolpyruvate + ADP + H+→pyruvate + ATP (EC 2.7.1.40)
DDA3937_RS10125	-1.1
DDA3937_RS12740	-0.2
D-lactate dehydrogenase (in reverse): pyruvate + NADH + H+→(R)-lactate + NAD+ (EC 1.1.1.28)
DDA3937_RS12295	-0.1
Malate dehydrogenase (in reverse): oxaloacetate + NADH + H+→(S)-malate + NAD+ (EC 1.1.1.37; 1.1.1.38)
DDA3937_RS02970	-0.4
DDA3937_RS07530	+0.3
DDA3937_RS08480	-0.8
DDA3937_RS13075	+0.5
Formate C-acetyltransferase (in reverse): pyruvate + coenzyme A→acetyl-CoA + formate (EC 2.3.1.54)
DDA3937_RS09650	-2.0
DDA3937_RS09655	-2.0
DDA3937_RS15785	-0.0
Acetaldehyde dehydrogenase (acetylating) (in reverse): acetyl-CoA + NADH + H+→acetaldehyde + coenzyme A + NAD+ (EC 1.2.1.10)
DDA3937_RS10360	+0.9
DDA3937_RS16335	-0.0
Citrate (Si)-synthase: acetyl-CoA + oxaloacetate + H2O→citrate + coenzyme A + H+ (EC 2.3.3.1; 2.3.3.16; 2.3.3.3)
DDA3937_RS06435	N.D.
formate + H+→CO2 + H2
DDA3937_RS07405	-1.0
DDA3937_RS07465	-0.3
Fumarate hydratase: (S)-malate→fumarate + H2O (EC 4.2.1.2)
DDA3937_RS04540	-0.3
DDA3937_RS10655	+0.2
Phosphate acetyltransferase: acetyl-CoA + phosphate→acetyl phosphate + coenzyme A (EC 2.3.1.8)
DDA3937_RS14385	-2.4
Acetate kinase (in reverse): acetyl phosphate + ADP→acetate + ATP (EC 2.7.2.1; 2.7.2.15)
DDA3937_RS10145	-0.2
DDA3937_RS14380	-3.2
Aconitate hydratase: citrate→cis-aconitate + H2O (EC 4.2.1.3)
DDA3937_RS12555	-0.1
DDA3937_RS17885	N.D.
Alcohol dehydrogenase (in reverse): acetaldehyde + NADH + H+→ethanol + NAD+ (EC 1.1.1.1)
DDA3937_RS01315	+0.2
DDA3937_RS03640	-0.4
DDA3937_RS09325	-0.0
DDA3937_RS10360	+0.9
DDA3937_RS11900	-0.0
DDA3937_RS17845	-0.2
Succinate dehydrogenase (ubiquinone): fumarate[in] + a menaquinol→succinate[in] + a menaquinone (EC 1.3.5.1)
DDA3937_RS18965	-1.3
DDA3937_RS18970	-0.9
DDA3937_RS18975	-0.7
DDA3937_RS18980	-2.5
Aconitate hydratase: cis-aconitate + H2O→D-threo-isocitrate (EC 4.2.1.3)
DDA3937_RS12555	-0.1
DDA3937_RS17885	N.D.
Isocitrate dehydrogenase (NADP(+)): D-threo-isocitrate + NADP+→CO2 + 2-oxoglutarate + NADPH (EC 1.1.1.42)
DDA3937_RS11470	N.D.

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information