MetaCyc Pathway: glycine degradation in Escherichia coli BW25113
| Reactions and Genes | LB Anaerobic with Cephalothin 0.0000078125 mM |
|---|---|
| remove | |
| glycine + NAD+ + a tetrahydrofolate→ammonium + a 5,10-methylenetetrahydrofolate + CO2 + NADH (EC 1.4.1.27) | |
| b0116 (lpd) | N.D. |
| b2905 (gcvT) | +1.0 |
| Glycine hydroxymethyltransferase (in reverse): glycine + a 5,10-methylenetetrahydrofolate + H2O→L-serine + a tetrahydrofolate (EC 2.1.2.1) | |
| b2551 (glyA) | N.D. |
| L-serine ammonia-lyase: L-serine→ammonium + pyruvate (EC 4.3.1.17) | |
| b1814 (sdaA) | -1.4 |
| b2797 (sdaB) | -1.1 |
| b3117 (tdcB) | +0.2 |
| b4471 (tdcG) | -0.2 |
Links:
Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information