MetaCyc Pathway: pyruvate fermentation to ethanol I in Escherichia coli BW25113
| Reactions and Genes | LB Anaerobic with Cephalothin 0.0000078125 mM |
|---|---|
| remove | |
| Formate C-acetyltransferase (in reverse): pyruvate + coenzyme A→acetyl-CoA + formate (EC 2.3.1.54) | |
| b0823 (ybiW) | +0.6 |
| b0824 (ybiY) | +0.1 |
| b0902 (pflA) | -3.1 |
| b0903 (pflB) | -0.1 |
| b2579 (yfiD) | +0.6 |
| b3951 (pflD) | +0.2 |
| b3952 (pflC) | -0.5 |
| b3114 (tdcE) | -0.2 |
| Acetaldehyde dehydrogenase (acetylating) (in reverse): acetyl-CoA + NADH + H+→acetaldehyde + coenzyme A + NAD+ (EC 1.2.1.10) | |
| b0351 (mhpF) | +0.1 |
| b1241 (adhE) | -1.9 |
| b2455 (eutE) | -0.0 |
| Alcohol dehydrogenase (in reverse): acetaldehyde + NADH + H+→ethanol + NAD+ (EC 1.1.1.1) | |
| b0325 (yahK) | -0.3 |
| b0356 (frmA) | -0.5 |
| b1241 (adhE) | -1.9 |
| b1478 (adhP) | +0.1 |
| b3253 (yhdH) | -1.5 |
| b4269 (yjgB) | -0.3 |
| b3589 (yiaY) | -0.1 |
Links:
- Pathway details at MetaCyc
- Fitness data for 17 genes
- All MetaCyc pathways for Escherichia coli BW25113
Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information