MetaCyc Pathway: L-isoleucine degradation II in Escherichia coli BW25113
| Reactions and Genes | LB Anaerobic with Cephalothin 0.0000078125 mM |
|---|---|
| remove | |
| Branched-chain-amino-acid transaminase: L-isoleucine + 2-oxoglutarate→(3S)-3-methyl-2-oxopentanoate + L-glutamate (EC 2.6.1.42) | |
| b3770 (ilvE) | -0.2 |
| Branched-chain-2-oxoacid decarboxylase: (3S)-3-methyl-2-oxopentanoate + H+→2-methylbutanal + CO2 (EC 4.1.1.72) | |
| No genes | |
| Alcohol dehydrogenase (in reverse): 2-methylbutanal + NADH + H+→2-methylbutanol + NAD+ (EC 1.1.1.1) | |
| b0325 (yahK) | -0.3 |
| b0356 (frmA) | -0.5 |
| b1241 (adhE) | -1.9 |
| b1478 (adhP) | +0.1 |
| b3253 (yhdH) | -1.5 |
| b4269 (yjgB) | -0.3 |
| b3589 (yiaY) | -0.1 |
Links:
Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information