MetaCyc Pathway: acetylene degradation (anaerobic) in Escherichia coli BW25113
| Reactions and Genes | LB Anaerobic with Cephalothin 0.0000078125 mM |
|---|---|
| remove | |
| Acetylene hydratase: acetylene + H2O→acetaldehyde (EC 4.2.1.112) | |
| No genes | |
| Acetaldehyde dehydrogenase (acetylating): acetaldehyde + coenzyme A + NAD+→acetyl-CoA + NADH + H+ (EC 1.2.1.10) | |
| b0351 (mhpF) | +0.1 |
| b1241 (adhE) | -1.9 |
| b2455 (eutE) | -0.0 |
| Alcohol dehydrogenase (in reverse): acetaldehyde + NADH + H+→ethanol + NAD+ (EC 1.1.1.1) | |
| b0325 (yahK) | -0.3 |
| b0356 (frmA) | -0.5 |
| b1241 (adhE) | -1.9 |
| b1478 (adhP) | +0.1 |
| b3253 (yhdH) | -1.5 |
| b4269 (yjgB) | -0.3 |
| b3589 (yiaY) | -0.1 |
| Phosphate acetyltransferase: acetyl-CoA + phosphate→acetyl phosphate + coenzyme A (EC 2.3.1.8) | |
| b2297 (pta) | -0.1 |
| b2458 (eutI) | -0.9 |
| Acetate kinase (in reverse): acetyl phosphate + ADP→acetate + ATP (EC 2.7.2.1; 2.7.2.15) | |
| b1849 (purT) | -0.0 |
| b2296 (ackA) | N.D. |
| b2460 (eutQ) | -0.1 |
| b2461 (eutP) | -0.0 |
| b3115 (tdcD) | -0.5 |
Links:
- Pathway details at MetaCyc
- Fitness data for 16 genes
- All MetaCyc pathways for Escherichia coli BW25113
Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information