MetaCyc Pathway: phenylethanol biosynthesis in Escherichia coli BW25113
| Reactions and Genes | LB Anaerobic with Furaltadone 0.000015625 mM |
|---|---|
| remove | |
| Aromatic-L-amino-acid decarboxylase: L-phenylalanine + H+→2-phenylethylamine + CO2 (EC 4.1.1.28; 4.1.1.53) | |
| No genes | |
| L-phenylalanine + dioxygen + H+ + H2O→phenylacetaldehyde + ammonium + CO2 + hydrogen peroxide (EC 4.1.1.109) | |
| No genes | |
| Primary-amine oxidase: 2-phenylethylamine + dioxygen + H2O→phenylacetaldehyde + ammonium + hydrogen peroxide (EC 1.4.3.21; 1.4.3.4) | |
| b1386 (tynA) | +0.4 |
| phenylacetaldehyde + NADPH + H+→2-phenylethanol + NADP+ | |
| No genes | |
| Alcohol dehydrogenase (in reverse): phenylacetaldehyde + NADH + H+→2-phenylethanol + NAD+ (EC 1.1.1.1) | |
| b0325 (yahK) | +0.2 |
| b0356 (frmA) | -0.1 |
| b1241 (adhE) | -0.6 |
| b1478 (adhP) | -0.4 |
| b3253 (yhdH) | -4.6 |
| b4269 (yjgB) | +0.3 |
| b3589 (yiaY) | +0.1 |
Links:
Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information