MetaCyc Pathway: galactitol degradation in Escherichia coli BW25113
| Reactions and Genes | LB Anaerobic with Cefoxitin 0.000003125 mM |
|---|---|
| remove | |
| galactitol[out] + an [HPr protein]-Nπ-phospho-L-histidine[in]→galactitol 1-phosphate[in] + an [HPr]-L-histidine[in] (EC 2.7.1.200) | |
| b2092 (gatC) | +2.7 |
| b2093 (gatB) | +0.8 |
| b2094 (gatA) | +0.7 |
| Galactitol-1-phosphate 5-dehydrogenase: galactitol 1-phosphate + NAD+→keto-D-tagatose 6-phosphate + NADH + H+ (EC 1.1.1.251) | |
| b2091 (gatD) | +0.5 |
| keto-D-tagatose 6-phosphate→D-tagatofuranose 6-phosphate (spontaneous) | |
| No genes | |
| Tagatose-6-phosphate kinase: D-tagatofuranose 6-phosphate + ATP→D-tagatofuranose 1,6-bisphosphate + ADP + H+ (EC 2.7.1.144) | |
| b1723 (pfkB) | +0.3 |
| b2095 (gatZ) | +1.6 |
| b2168 (fruK) | +1.4 |
| b3132 (kbaZ) | +0.0 |
| b3916 (pfkA) | +0.1 |
| Tagatose-bisphosphate aldolase: D-tagatofuranose 1,6-bisphosphate→glycerone phosphate + D-glyceraldehyde 3-phosphate (EC 4.1.2.40) | |
| b2095 (gatZ) | +1.6 |
| b2096 (gatY) | +3.7 |
| b3132 (kbaZ) | +0.0 |
| b3137 (kbaY) | +0.0 |
Links:
- Pathway details at MetaCyc
- Fitness data for 11 genes
- All MetaCyc pathways for Escherichia coli BW25113
Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information