MetaCyc Pathway: hydrogen sulfide biosynthesis II (mammalian) in Escherichia coli BW25113
| Reactions and Genes | LB Aerobic with Novobiocin 0.0000625 mM |
|---|---|
| remove | |
| Homocysteine desulfhydrase: L-homocysteine + H2O→hydrogen sulfide + 2-oxobutanoate + ammonium (EC 4.4.1.2) | |
| No genes | |
| Cystathionine gamma-lyase: L-cysteine + H2O→hydrogen sulfide + ammonium + pyruvate (EC 4.4.1.1; 4.4.1.28) | |
| b1622 (malY) | -0.4 |
| b2414 (cysK) | +0.2 |
| b2421 (cysM) | +1.6 |
| b3008 (metC) | -0.2 |
| b3708 (tnaA) | -0.1 |
| b4470 (yhaM) | -0.1 |
| Cystathionine beta-synthase: L-cysteine + H2O→hydrogen sulfide + L-serine (EC 4.2.1.22) | |
| No genes | |
| Cystathionine beta-synthase: 2 L-cysteine→hydrogen sulfide + lanthionine (EC 4.2.1.22) | |
| No genes | |
| Cystathionine beta-synthase: L-cysteine + L-homocysteine→hydrogen sulfide + L-cystathionine (EC 4.2.1.22) | |
| No genes | |
| 2 L-homocysteine→hydrogen sulfide + L-homolanthionine | |
| No genes | |
Links:
Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information