MetaCyc Pathway: polyhydroxybutanoate biosynthesis in Pseudomonas simiae WCS417

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Reactions and Genes 2-Deoxy-D-ribonic lithium salt 10 mM (C)
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Acetyl-CoA C-acyltransferase:
2 acetyl-CoA→acetoacetyl-CoA + coenzyme A (EC 2.3.1.16; 2.3.1.9)
PS417_06710 -0.6
PS417_07580 N.D.
PS417_10515 -3.8
PS417_13855 +0.4
PS417_15175 N.D.
PS417_19210 -0.2
PS417_21220 -0.3
PS417_03145 -0.2
Acetoacetyl-CoA reductase (in reverse):
acetoacetyl-CoA + NADPH + H+→(3R)-3-hydroxybutanoyl-CoA + NADP+ (EC 1.1.1.36)
No genes
(3R)-3-hydroxybutanoyl-CoA + poly-[(R)-3-hydroxybutanoate]→poly-[(R)-3-hydroxybutanoate] + coenzyme A (EC 2.3.1.304)
PS417_05940 -0.1

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information