MetaCyc Pathway: pyruvate fermentation to acetone in Pseudomonas simiae WCS417

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Reactions and Genes 2-Deoxy-D-ribonic lithium salt 10 mM (C)
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Pyruvate synthase:
pyruvate + coenzyme A + 2 an oxidized ferredoxin [iron-sulfur] cluster→acetyl-CoA + CO2 + H+ + 2 a reduced ferredoxin [iron-sulfur] cluster
(EC 1.2.7.1)
No genes
Acetyl-CoA C-acyltransferase:
2 acetyl-CoA→acetoacetyl-CoA + coenzyme A
(EC 2.3.1.16; 2.3.1.9)
PS417_06710 -0.6
PS417_07580 N.D.
PS417_10515 -3.8
PS417_13855 +0.4
PS417_15175 N.D.
PS417_19210 -0.2
PS417_21220 -0.3
PS417_03145 -0.2
Butyrate--acetoacetate CoA-transferase (in reverse):
acetoacetyl-CoA + butanoate→acetoacetate + butanoyl-CoA
(EC 2.8.3.9)
No genes
Butyrate--acetoacetate CoA-transferase (in reverse):
acetoacetyl-CoA + acetate→acetoacetate + acetyl-CoA
(EC 2.8.3.9)
No genes
Acetoacetate decarboxylase:
acetoacetate + H+→acetone + CO2
(EC 4.1.1.4)
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information